петък, 20 август 2021 г.

Weekly Digest: New diabetes clinical trial (18 items)

New diabetes clinical trial: Effect of Oral Anti-diabetic Medication on Liver Fat in Subjects With Type II Diabetes and Non-alcoholic Fatty Liver

Published on: July 26, 2021 at 07:00PM
Conditions:   Diabetes Mellitus, Type 2;   NASH - Nonalcoholic Steatohepatitis;   NAFLD
Interventions:   Drug: Pioglitazone;   Drug: Empagliflozin;   Drug: Pioglitazone + Empagliflozin
Sponsor:   Getz Pharma
Not yet recruiting
https://clinicaltrials.gov/ct2/show/NCT04976283?term=diabetes&sfpd_d=14 July 26, 2021 at 08:22PM

via ClinicalTrials.gov


New diabetes clinical trial: Echocardiographic Assessment of the Impact of Diabetes and Prognostic Analysis of Heart Transplantation

Published on: July 26, 2021 at 07:00PM
Condition:   Heart Transplant
Intervention:  
Sponsors:   Xie Mingxing;   Second Affiliated Hospital, School of Medicine, Zhejiang University;   Shanghai Zhongshan Hospital;   Wuhan Asia Heart Hospital;   Guangdong Provincial People's Hospital;   Henan Provincial People's Hospital
Not yet recruiting
https://clinicaltrials.gov/ct2/show/NCT04976517?term=diabetes&sfpd_d=14 July 26, 2021 at 08:22PM

via ClinicalTrials.gov


New diabetes clinical trial: The PREPARED Trial

Published on: July 26, 2021 at 07:00PM
Conditions:   Diabetes Mellitus, Type 2;   Electronic Health Record;   Primary Health Care;   Reproductive Behavior
Interventions:   Behavioral: Medication Reconciliation (MedRec) Tool;   Behavioral: Provider Best Practices Alert (BPA) and Decision Support;   Behavioral: PREPSheet;   Behavioral: Text Messaging
Sponsors:   Northwestern University;   Northwestern Memorial Hospital;   AllianceChicago
Not yet recruiting
https://clinicaltrials.gov/ct2/show/NCT04976881?term=diabetes&sfpd_d=14 July 26, 2021 at 08:22PM

via ClinicalTrials.gov


New diabetes clinical trial: The Influence of Personality Characteristics and Emotions on Blood Glucose Levels Among Type 1 Diabetes Mellitus Patients

Published on: July 27, 2021 at 07:00PM
Condition:   Significant Correlation Between Baseline Personality Characteristics, Changing Emotions Throughout the Day, and Glycemic Levels in Patients With T1DM
Intervention:  
Sponsors:   Tel-Aviv Sourasky Medical Center;   Rambam Health Care Campus;   Tel Aviv University
Completed
https://clinicaltrials.gov/ct2/show/NCT04978441?term=diabetes&sfpd_d=14 July 27, 2021 at 06:22PM

via ClinicalTrials.gov


New diabetes clinical trial: Intervention for High-normal Blood Pressure in Adults With Type 2 Diabetes-----renal Substudy

Published on: July 27, 2021 at 07:00PM
Conditions:   Diabetes Mellitus, Type 2;   Blood Pressure
Interventions:   Drug: Allisartan Isoproxil;   Drug: Amlodipine
Sponsor:   Guangdong Provincial People's Hospital
Not yet recruiting
https://clinicaltrials.gov/ct2/show/NCT04978649?term=diabetes&sfpd_d=14 July 27, 2021 at 06:22PM

via ClinicalTrials.gov


New diabetes clinical trial: Closing the Loop in Adults With Type 1 Diabetes (CLEAR)

Published on: July 27, 2021 at 07:00PM
Condition:   Type 1 Diabetes
Interventions:   Device: CamAPS HX;   Device: Standard insulin pump therapy with CGM
Sponsors:   University of Cambridge;   Cambridge University Hospitals NHS Foundation Trust
Not yet recruiting
https://clinicaltrials.gov/ct2/show/NCT04977908?term=diabetes&sfpd_d=14 July 27, 2021 at 06:22PM

via ClinicalTrials.gov


New diabetes clinical trial: Sleep and Chronotype in Children With Type 1 Diabetes

Published on: July 27, 2021 at 07:00PM
Condition:   Diabetes Mellitus, Type 1
Intervention:  
Sponsors:   Marmara University;   The Scientific and Technological Research Council of Turkey
Enrolling by invitation
https://clinicaltrials.gov/ct2/show/NCT04978662?term=diabetes&sfpd_d=14 July 27, 2021 at 06:22PM

via ClinicalTrials.gov


New diabetes clinical trial: Biomarkers of Heterogeneity in Type 1 Diabetes

Published on: July 27, 2021 at 07:00PM
Condition:   Type 1 Diabetes
Intervention:  
Sponsors:   Diabeter Nederland BV;   University Medical Center Groningen
Active, not recruiting
https://clinicaltrials.gov/ct2/show/NCT04977635?term=diabetes&sfpd_d=14 July 27, 2021 at 06:22PM

via ClinicalTrials.gov


New diabetes clinical trial: A Study for Post-Marketing Surveillance of Nesina® Tablet Monotherapy or Combination Therapy in Participants With Type 2 Diabetes (T2DM) in South Korea

Published on: July 28, 2021 at 07:00PM
Condition:   Type 2 Diabetes Mellitus
Intervention:   Drug: Alogliptin Benzoate
Sponsor:   Takeda
Completed
https://clinicaltrials.gov/ct2/show/NCT04980040?term=diabetes&sfpd_d=14 July 28, 2021 at 10:22PM

via ClinicalTrials.gov


New diabetes clinical trial: Comparing Semaglutide Versus Placebo on Intestinal Barrier Function in Type 2 Diabetes Mellitus (SIB)

Published on: July 28, 2021 at 07:00PM
Conditions:   Type 2 Diabetes;   Chronic Inflammation;   Intestinal Permeability
Interventions:   Drug: Semaglutide;   Drug: Placebo
Sponsors:   University of Colorado, Denver;   Novo Nordisk A/S
Not yet recruiting
https://clinicaltrials.gov/ct2/show/NCT04979130?term=diabetes&sfpd_d=14 July 28, 2021 at 10:22PM

via ClinicalTrials.gov


New diabetes clinical trial: Evaluation of the Safety and Efficacy of Insulin Glargine 300 U/ml (Gla-300) in Insulin-naïve Patients With Type 2 Diabetes Mellitus Uncontrolled on Oral Antihyperglycemic Drugs

Published on: July 28, 2021 at 07:00PM
Condition:   Type 2 Diabetes Mellitus
Intervention:   Drug: Insulin glargine (U300)
Sponsor:   Sanofi
Not yet recruiting
https://clinicaltrials.gov/ct2/show/NCT04980027?term=diabetes&sfpd_d=14 July 28, 2021 at 10:22PM

via ClinicalTrials.gov


New diabetes clinical trial: A Post-Marketing Surveillance Study on NesinaAct® Tablet Use Among Type 2 Diabetes Mellitus Participants in Korea

Published on: July 28, 2021 at 07:00PM
Condition:   Type 2 Diabetes Mellitus
Intervention:   Drug: NesinaAct® Tablet
Sponsor:   Takeda
Completed
https://clinicaltrials.gov/ct2/show/NCT04980014?term=diabetes&sfpd_d=14 July 28, 2021 at 10:22PM

via ClinicalTrials.gov


New diabetes clinical trial: Prevalence of Hyperandrogenism in Type 1 Diabetes

Published on: July 28, 2021 at 07:00PM
Conditions:   Type 1 Diabetes;   Polycystic Ovary Syndrome;   Hyperandrogenism;   Hirsutism;   Oligomenorrhea;   Ovulation Disorder
Interventions:   Other: Clinical hyperandrogenism assessment;   Diagnostic Test: Total testosterone (ng/dL);   Diagnostic Test: A1c (%);   Diagnostic Test: Total cholesterol;   Other: Body mass index (BMI) (kg/m2);   Diagnostic Test: Frequency of chronic vascular complications [n (%)];   Diagnostic Test: Polycystic ovary morphology;   Diagnostic Test: Cardiovascular autonomic reflex tests (CARTs);   Diagnostic Test: Sex hormone-binding globulin (SHBG) (nmol/L);   Diagnostic Test: Dehydroepiandrosterone-sulphate (IQL) (ng/mL);   Other: Waist circumference (cm);   Other: Waist-to-hip ratio;   Other: Body composition;   Diagnostic Test: Mean glucose (mg/dL);   Diagnostic Test: Time in target range (hours);   Diagnostic Test: Time in hyperglycemia (hours);   Other: Insulin dose (UI/Kg);   Other: Insulin sensitivity;   Diagnostic Test: High-density lipoprotein (HDL) (mg/dL);   Diagnostic Test: Low-density lipoprotein (LDL) (mg/dL);   Diagnostic Test: Triglycerides (mg/dL)
Sponsors:   Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal;   Hospital Universitario Ramon y Cajal;   Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders;   University of Alcala;   Instituto de Salud Carlos III
Recruiting
https://clinicaltrials.gov/ct2/show/NCT04979377?term=diabetes&sfpd_d=14 July 28, 2021 at 10:22PM

via ClinicalTrials.gov


New diabetes clinical trial: Efficacy and Safety of Bifidobacterium Quadruple Live Tablets in Patients With T2DM and Constipation

Published on: July 29, 2021 at 07:00PM
Condition:   Type 2 Diabetes Mellitus With Complication
Interventions:   Drug: Bifidobacterium, Lactobacillus, Enterococcus and Bacillus Cereus Tablets, Live;   Drug: Siliankang simulating tablets
Sponsors:   Peking Union Medical College Hospital;   First Affiliated Hospital of Harbin Medical University;   The Affiliated Hospital of Inner Mongolia Medical University;   Affiliated Hospital of Chengde Medical University;   The First Affiliated Hospital of Zhengzhou University;   Chinese Academy of Sciences;   Hangzhou Grand Biologic Pharmaceutical, Inc.
Not yet recruiting
https://clinicaltrials.gov/ct2/show/NCT04982380?term=diabetes&sfpd_d=14 July 29, 2021 at 05:23PM

via ClinicalTrials.gov


New diabetes clinical trial: Research Study to Look at How Well Cagrilintide Together With Semaglutide Works in People With Type 2 Diabetes

Published on: July 29, 2021 at 07:00PM
Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Semaglutide 2.4 mg;   Drug: Cagrilintide 2.4 mg;   Drug: Placebo (semaglutide);   Drug: Placebo (cagrilintide)
Sponsor:   Novo Nordisk A/S
Not yet recruiting
https://clinicaltrials.gov/ct2/show/NCT04982575?term=diabetes&sfpd_d=14 July 29, 2021 at 05:23PM

via ClinicalTrials.gov


New diabetes clinical trial: Diabetes teleMonitoring of Patients in Insulin Therapy

Published on: July 29, 2021 at 07:00PM
Condition:   Type 2 Diabetes Treated With Insulin
Intervention:   Device: Telemonitoring
Sponsors:   Aalborg University Hospital;   Steno Diabetes Center Sjaelland;   Novo Nordisk A/S;   Glooko;   DexCom, Inc.
Not yet recruiting
https://clinicaltrials.gov/ct2/show/NCT04981808?term=diabetes&sfpd_d=14 July 29, 2021 at 05:23PM

via ClinicalTrials.gov


New diabetes clinical trial: Feasibility of Yoga for Type-2 Diabetes

Published on: July 29, 2021 at 07:00PM
Condition:   Type2 Diabetes
Interventions:   Behavioral: Iyengar yoga;   Behavioral: Standard Exercise;   Behavioral: Nutrition Counseling
Sponsor:   The Miriam Hospital
Not yet recruiting
https://clinicaltrials.gov/ct2/show/NCT04982640?term=diabetes&sfpd_d=14 July 29, 2021 at 05:24PM

via ClinicalTrials.gov


New diabetes clinical trial: Diabetes Complications and the Risk of Cardiovascular and Cerebrovascular Diseases

Published on: July 30, 2021 at 07:00PM
Conditions:   Diabetes Complications;   Cardiovascular Diseases;   Cerebrovascular Disease
Intervention:   Other: no intervention
Sponsor:   Second Affiliated Hospital, School of Medicine, Zhejiang University
Not yet recruiting
https://clinicaltrials.gov/ct2/show/NCT04983277?term=diabetes&sfpd_d=14 July 30, 2021 at 08:22PM

via ClinicalTrials.gov


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